N-acetyl-l-cysteine and lipoic acid

Supplemetantion that increases extracellular L-cysteine by decreasing levels of extracellular cystine, as do n-acetyl-l-cysteine  and lipoic acid, must be avoided. Cystine, has to be available to enter cells via the cystine/glutamate antiporter so l-glutamate can be transported out. Any supplement that decreases extracellular cystine levels is very dangerous.  Blocking the cystine/glutamate antiporter induces ferroptosis which can kill cells.

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