The Central Dogma of Biology – Information passes from DNA to proteins via RNA, but proteins cannot pass the information back to DNA.
While DNA sequences are not altered by environmental changes transcription and/or translation of genes can be altered by changes in enzyme activities and enzyme levels through whereby genes become hypermethylated. Dysregulation of TET enzymes that demethylate DNA in embryos could leave a path open for transgenerational epigenetic inheritances.
