One might hold that all vitamin deficiency angles in schizophrenia have been thoroughly investigated, found wanting and that researches have just moved on. The view might be that the very rococo hypotheses of psychiatric genetics, for example, have only been resorted to only after all simpler theories have been falsified. This is not the case. A search on PubMed of “coenzyme a” and schizophrenia only pulls up 21 articles where none of the articles investigate coenzyme A levels in schizophrenia.
As it turns out supplementation with pantothenic acid, from which coenzyme A is synthesized, is a precondition of the treatment of the negative symptoms of schizophrenia which are the worst symptoms of schizophrenia. Treatment with pantothenic acid alone will not be sufficient to treat the negative symptoms of schizophrenia. Sulbutiamine, coenzyme Q10 and biotin are also required to treat the negative symptoms of schizophrenia.