Gut microbiota are dependent on the environment of the gut for nutrients. If metabolic processes are dysregulated in the gut this will affect nutrients available in the gut. Some species of microbiota could be favored by various gut metabolic dysregulations while other microbiota could be disfavored. Certain microbiotic ecosystems could have direct effects, for example, causing diarrhea while other microbiotic ecoystems could only be markers for iron dysregulation in the gut which can have systematic effects.
Iron in the gut is a nutrient in the gut that affects the microbiotic ecosystem of the gut. Gut microbiota and iron are held to be crucial actors in health where many species (see Table) of gut microbiota are affected by iron supplementation.
Differences in gut microbiota could largely be a marker for iron dysregulation in the gut. Lots of substances in the diet bind with iron which could be affecting gut microbiota. Probiotics can affect iron metabolism in the gut. Lactobacillus plantarum 299v can increase iron absorption. A meta-analysis indicates that Lactobacillus plantarum 299v increases iron absorption. Lactobacillus plantarum 299v does not require iron which could make iron more available in the gut besides assisting with the absorption of iron via more iron being available to be absorbed. Bifidobacteria,. another beneficial microorganism in the gut, requires iron.
In sum gut microbiota is dysregulated in so many illnesses as iron metabolism in the gut is dysregulated in so many illnesses.