Decreasing DNA methylation vs. increasing DNA demethylation

DNA methylation is necessary to life. Just decreasing DNA methylation by main force by decreasing levels of enzymes that methylate DNA could have unpredictable and undesirable effects. Increasing the ability of TET enzymes to demethylate DNA would seem to be a more benign approach to decreasing DNA methylation. Presumably TET enzymes are regulated and and only called into play when necessary..

Leave a Reply

Your email address will not be published.

This site uses Akismet to reduce spam. Learn how your comment data is processed.